On his farewell tour, Simon "penalized" himself for wrongly performing the lyrics to another song by singing this song, which he confesses to hating.
The theme song to the American children's TV show H.R. Pufnstuf, originally composed by Sid and Marty Krofft, was found to closely mimic "The 59th Street Bridge Song" after Simon sued; his writing cr was subsequently added to the H.R. Pufnstuf theme.
The Coolies cover it on their 1986 album dig..?, along with eight other tongue-in-cheek covers of Simon & Garfunkel classics.
Pizzicato Five made a Japanese-language version of the song, included on both the single The Audrey Hepburn Complex and the album Pizzicatomania!.
The song was covered by the Boston band Jim's Big Ego on the album Don't Get Smart.
The Grateful Dead were known to have sampled portions of the song in their music. The most notable instance was within the performance of "Dark Star" on 13 February 1970 at the Fillmore East in New York, NY on the Dick's Picks Volume 4 album.[verification needed]
O.A.R. has been covering this song in concert since 2002. They play their own arrangement which always serves as an intro to fan favorites "That Was a Crazy Game of Poker" or "City on Down".
The song was parodied by Bob Rivers as "Feelin' Boobies".
Tori Amos performed the song at several of her concerts in 2005.
The song was used in an episode of The Simpsons (season 6, episode 25) called "Who Shot Mr. Burns? (Part One)". Mr. Burns alludes to the song, saying, "Hello lamppost, whatcha knowin'? I've come to watch your power flowin'."
The song was used in the trailer for Hal Ashby's 1975 comedy-drama Shampoo for which Paul Simon composed the original score.
The song was used in the season 3 premiere of The Leftovers (season 3, episode 1) called "The Book of Kevin". Protagonist Kevin Garvey asphyxiates himself with plastic wrap and duct tape in his room as the song plays.