Lupan-3beta,20-diol synthase

Lupan-3beta,20-diol synthase
Identifiers
EC no.4.2.1.128
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Lupan-3beta,20-diol synthase (EC 4.2.1.128, LUP1 (gene)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (lupan-3beta,20-diol forming).[1][2] This enzyme catalyses the following chemical reaction

lupan-3beta,20-diol (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O

The reaction occurs in the reverse direction.

References[]

  1. ^ Segura MJ, Meyer MM, Matsuda SP (July 2000). "Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol". Organic Letters. 2 (15): 2257–9. doi:10.1021/ol006016b. PMID 10930257.
  2. ^ Kushiro T, Hoshino M, Tsutsumi T, Kawai K, Shiro M, Shibuya M, Ebizuka Y (November 2006). "Stereochemical course in water addition during LUP1-catalyzed triterpene cyclization". Organic Letters. 8 (24): 5589–92. doi:10.1021/ol062310d. PMID 17107079.

External links[]