Sir Christopher Martin Dobson FRS FMedSci FRSC (8 October 1949 – 8 September 2019) was a British  chemist, who was the John Humphrey Plummer Professor of Chemical and Structural Biology in the Department of Chemistry at the University of Cambridge, and Master of St John's College, Cambridge.
Early life and education [ ]
Dobson was born on 8 October 1949 in
Rinteln, Germany, where his father, Arthur Dobson was commissioned as an officer.  Both Arthur Dobson and Christopher Dobson's mother, Mabel Dobson (née Pollard), were originally from  Bradford in Yorkshire and had left school at age 14. Dobson had two older siblings, Graham and Gillian.  Due to his father's postings, Dobson also lived in  Lagos, Nigeria.
Christopher Dobson was educated at
Hereford Cathedral Junior School, and then Abingdon School from 1960 until 1967.  He completed a  Master of Arts and Doctor of Philosophy at the  University of Oxford, where he was a student of Keble College, Oxford and Merton College, Oxford.
Research and career [ ]
Dobson's research largely focused on
protein folding and protein misfolding, and its association with medical disorders particularly Alzheimer's disease and Parkinson's disease. By applying chemical and biophysical techniques, Dobson investigated links between protein structure, function, and disease.
He is well known for his serendipitous discovery that ordinary proteins can misfold and aggregate to form
"A postdoc who left his sample of an unfolded protein in an NMR [nuclear magnetic resonance] spectrometer over a long weekend discovered, on his return, that it had turned into a gel. We were curious about this phenomenon and found that the NMR tube was full of amyloid fibrils that we then thought were associated only with diseases".
Christopher M. Dobson, 
Dobson authored and co-authored over 800 papers and review articles,
including 38 in  , Nature and Science Cell, which have been cited over 100,000 times. As of 2019 his  H-index is 153.
research fellowships at Merton College, Oxford and then Linacre College, Oxford before working at Harvard University. He returned to Oxford in 1980 as a Fellow of Lady Margaret Hall, Oxford and as a University Lecturer in Chemistry, later receiving promotions to Reader, then Professor of Chemistry in 1996. 
Dobson moved to the
University of Cambridge in 2001 as the John Humphrey Plummer Professor of Chemical and Structural Biology. In 2007, he became the Master of St John's College, Cambridge, a post which he held until his death in September 2019. 
In 2012, Dobson founded the Cambridge Centre for Misfolding Diseases,
which is currently based in the Chemistry of Health building at the Department of Chemistry at the University of Cambridge.  
In 2016, Chris Dobson co-founded Wren Therapeutics, a biotechnology start-up company whose mission is to find new therapeutics for Alzheimer's disease.
 Awards and honours [ ]
knighted in the 2018 Queen's Birthday Honours for his contributions to science and higher education.   In 2009, Dobson was awarded the  Royal Medal by the Royal Society "for his outstanding contributions to the understanding of the mechanisms of protein folding and mis-folding, and the implications for disease", and in 2014 he received both the Heineken Prize for Biochemistry and Biophysics and the Feltrinelli International Prize for Medicine. Dobson was elected a Fellow of the Royal Society (FRS) in 1996. His nomination reads: 
Dobson is distinguished for his studies, principally using
NMR methods, of the structures and dynamics of proteins in solution. Such studies include those on lysozyme, with which he demonstrated many methodological advances, interleukin-4, with which he established for the first time the topology of the important family of haemopoietic helical cytokines, and urokinase-type plasminogen activator, with which he elucidated the dynamic characteristics of multidomain fibrinolytic proteins, Dobson is a pioneer in the application of NMR methods to the problem of protein folding, which is now the major theme of his work. His studies on lysozyme are resulting in one of the most detailed descriptions of a folding pathway for a protein. Dobson has explored the properties and reactions of molecules in solids by means of NMR spectroscopy, including proteins, organometallic compounds, inorganic paramagnets and the silicaceous components of hydraulic materials. Notable here are analyses of the nature and origin of dynamic properties in molecular solids, and their relationship to structure and reactivity.
Dobson's other accolades include:
Corday-Morgan Medal and Prize, The Royal Society of Chemistry, 1981 
Howard Hughes Medical Institute International Research Scholar, 1992  Brunauer Award,
American Ceramic Society, 1996  Elected a
Fellow of the Royal Society (FRS) in 1996  Dewey and Kelly Award,
University of Nebraska, 1997  National Lecturer,
American Biophysical Society, 1998  Member of the
European Molecular Biology Organisation (EMBO) 1999  Interdisciplinary Award, The Royal Society of Chemistry, 1999
 Doctor Honoris Causa, University of Leuven, Belgium, 2001
 Presidential Visiting Scholar, University of California San Francisco, 2001
 Bijvoet Medal,
Bijvoet Center for Biomolecular Research, University of Utrecht, The Netherlands, 2002  Silver Medal, Italian Society of Biochemistry, 2002
Royal Society Bakerian Lecturer, 2003  Stein and Moore Award, The Protein Society, 2003
 Honorary Member, National Magnetic Resonance Society of India, 2004
 Elected a
Fellow of the Academy of Medical Sciences (FMedSci) in 2005  Honorary Doctor of Medicine,
Umea University, Sweden, 2005 
Davy Medal, The Royal Society, 2005  Hans Neurath Award, The Protein Society, 2006
 Honorary Doctor of Medicine, University of Florence, Italy, 2006
 Doctor Honoris Causa, University of Liège, Belgium, 2007
 Sammet Guest Professor, Johann Wolfgang Goethe University, Frankfurt, 2007
 Foreign Honorary Member of the American Academy of Arts and Sciences, 2007
 Fellow of the International Society of Magnetic Resonance, 2008
 Honorary Fellow, Linacre College, University of Oxford, 2008
 Honorary Fellow, Lady Margaret Hall, University of Oxford, 2008
 Honorary Fellow, Merton College, University of Oxford, 2009
 Honorary Fellow, Keble College, University of Oxford, 2009
 Royal Medal, The Royal Society, 2009
 Honorary Fellow of the Chemical Council of India, 2010
 Khorana Award, The Royal Society of Chemistry, 2010
 Honorary Doctorate of Science, King's College London, 2012
 Honorary Fellow, Trinity College Dublin, 2013
 Foreign Associate of the US National Academy of Sciences, 2013
 Honorary Fellow, Darwin College, University of Cambridge, 2014
Heineken Prize for Biochemistry and Biophysics, Royal Netherlands Academy of Arts and Sciences (KNAW), 2014 
Antonio Feltrinelli International Prize for Medicine, Accademia Nazionale dei Lincei, Rome, 2014  Member of the American Philosophical Society, 2018 
Mentorship [ ]
Dobson mentored and supervised many notable
PhD students and post-doctoral researchers, many of whom became renowned experts in their own field. These include:
Personal life [ ]
Dobson met his wife, Dr Mary Dobson (née Schove) at
Merton College at the University of Oxford. They had two sons, Richard and William.  
He died on 8 September 2019, from cancer, at
Royal Marsden Hospital in Sutton, near Surrey.
References [ ]
^ a b c d
Anon (2014). "DOBSON, Sir Christopher (Martin)". . Who's Who ukwhoswho.com (online Oxford University Press ed.). A & C Black, an imprint of Bloomsbury Publishing plc. doi: 10.1093/ww/9780199540884.013.U13819. (subscription or UK public library membership required) (subscription required)
^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad
"Chris Dobson – CV" . Retrieved . 11 September 2019
^ a b c d e f g h i j k
"Professor Sir Chris Dobson obituary". The Times. 12 September 2019. ISSN 0140-0460 . Retrieved . 13 September 2019
"Chemistry Prizes" (PDF). The Abingdonian.
Dobson, Christopher Martin (1975). . The conformation of lysozyme in solution ora.ox.ac.uk (DPhil thesis). University of Oxford. OCLC 500426925. EThOS uk.bl.ethos.453735.
"Professor Sir Chris Dobson obituary". The Times. 12 September 2019.
^ a b c d
"Professor Sir Christopher Dobson, master of St John's College, Cambridge, dies at 69". Cambridge Independent. 9 September 2019 . Retrieved . 9 September 2019
^ a b
Chris Dobson's publications indexed by the Scopus bibliographic database. (subscription required)
^ a b c
"Tributes paid to Master of St John's College who has died age 69". St John's College Cambridge . Retrieved . 9 September 2019
"New research facility for neurodegenerative disorders opened in Cambridge". University of Cambridge. 21 September 2018 . Retrieved . 9 September 2019
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"Knighthood for Prof Christopher Dobson, master of St John's College, in recognition of ground-breaking Alzheimer's research". Cambridge Independent. 8 June 2018 . Retrieved . 9 September 2019
"Cambridge spinout grabs $23M round to launch a new campaign to tackle protein misfolding". Endpoints News . Retrieved . 9 September 2019
"Knighthood for eminent scientist Sir Christopher Dobson". Lady Margaret Hall . Retrieved . 9 September 2019
^ a b
Anon (1996). "Sir Christopher Dobson FMedSci FRS". royalsociety.org. London: Royal Society. One or more of the preceding sentences incorporates text from the royalsociety.org website where:
"All text published under the heading 'Biography' on Fellow profile pages is available under
Creative Commons Attribution 4.0 International License.” -- Royal Society Terms, conditions and policies at the Wayback Machine (archived 11 November 2016)
"EC/1996/06: Dobson, Christopher Martin". London: The Royal Society. Archived from the original on 30 September 2014 . Retrieved . 30 September 2014
"Bijvoet Medal". Bijvoet Center for Biomolecular Research. Archived from the original on 12 September 2017 . Retrieved . 12 September 2017
"Master receives Honorary Degree from King's College London | StJohns".
"Fellows & Scholars : Trinity College Dublin, the University of Dublin, Ireland".
"2013 NAS Members and Foreign Associates Elected".
"Christopher M. Dobson – KNAW".
"Feltrinelli International Prize awarded to Chris Dobson | Department of Chemistry".
"Election of New Members at the 2018 Spring Meeting | American Philosophical Society".
"Paying tribute to Chris Dobson". www.rsc.org . Retrieved . 16 September 2019
"Membership to Royal Society" . Retrieved . 27 September 2019
Cait MacPhee [@sciorama] (13 September 2019). "Chris Dobson was a vocal and practical advocate of women in science before it was cool. The number of women he employed or appointed in Oxford led to us being called "Dobettes" (yes, we knew what you called us, you pricks)" (Tweet) . Retrieved – via 27 September 2019 Twitter.
"Membership to Royal Society of Chemistry" . Retrieved . 6 October 2019
"Membership to the National Academy of Sciences of the US".
"Membership to Academia Europaea" . Retrieved . 27 September 2019
"Citation metrics at Scopus" . Retrieved . 27 September 2019
"Membership to Academia Europaea" . Retrieved . 6 October 2019
"Citation metrics at Scopus" . Retrieved . 6 October 2019