In December 2007, it was re-released in a new remixed version as a digital download. This was the third and final single released from the album Get the Party Started. The single features a remix from Pink Pound and two instrumental remixes that were not included on the album release. Unlike the previous two singles this track featured a remix of a previous released recording, the vocal track was taken from a session recorded in 1984 for the album I Am What I Am. There was no promotion undertaken for the single and no video was made to support the release.
The song appeared in Muriel Cigar commercials in the 1970s, sung by Edie Adams. A modified version of the tune entreated the viewer to "...spend a little dime with me", referring to the price of a Muriel Cigar.
In an episode of British Asian sketch comedy show Goodness Gracious Me, the cast perform a parody of the song called "Big Spinster".
In the Discworld Noir computer game the 'Troll Saphire' performed a parody of "Big Spender", with the opening lyrics as "The minute you walked through the wall, I could tell that you were a troll of destruction"
In the "Viva Mars Vegas" episode of Futurama, a parody version is played of "Big Spender", with the lyrics as "Hey Rich Lobster", when Dr. Zoidberg shows up at a casino on Mars with millions of dollars to spend and lose.
A controversial video with flight attendants entreating an elite frequent flier made news in February 2019, generating protest from the flight attendants' union.
A parody appeared on a musical segment of SNL on Helloween of 2020 called "Big Spreader", referring to COVID-19