10/90 gap

The 10/90 gap is the term adopted by the Global Forum for Health Research to highlight the finding by the Commission on Health Research for Development in 1990, that less than 10% of worldwide resources devoted to health research were put towards health in Developing Countries, where over 90% of all preventable deaths worldwide occurred.[1] Every year, the spread of disease suffered in both rich and poor countries converges. According to the World Health Organization (WHO), the most prevalent diseases consist of cardiovascular disease, cancer and diabetes. These diseases now[when?] account for 45% of the global health burden and is the culprit for up to 85% of deaths in low-income countries. The 10/90 Gap focuses on joining organisations together to reduce these statistics.[2]

Disease and the 10/90 gap[]

A substantial portion of diseases, most prevalent in impoverished or developing countries, are those which are preventable and/or treatable.[3] The World Health Organization (2004) stated in their world health report that an estimated eight million individuals die prematurely, from diseases and conditions that can be cured, every year. These deaths contribute to approximately one third of all human deaths in the world, each year.[3] Table 1 lists several of these curable diseases.

Table 1: Causes of avoidable deaths.[3]

Conditions Leading to Avoidable Deaths Deaths in 2002
Respiratory infections (mainly pneumonia) 3,963,000
HIV/AIDS 2,777,000
Perinatal conditions 2,462,000
Diarrhoea 1,798,000
Tuberculosis 1,566,000
Malaria 1,272,000
Childhood diseases (mainly measles) 1,124,000
Maternal conditions 510,000
Malnutrition 485,000
Sexually transmitted diseases 180,000
Meningitis 173,000
Hepatitis 157,000
Tropical diseases 129,000

Strategies for change[]

Global health organisations across the globe have explicitly made research into health their priority. In 2000, World Health Organization established the Commission on Macroeconomics and Health, who in their 2001 report, verified the relationship between poverty and disease and discussed the benefit of investment on the economic climates of developing countries.[4] Possible strategies that can be implanted to help reduce the 10/90 gap are, policies prioritizing funding for health research, also developing capacities of credible public and private health research institutions.[5] Also activities of international NGOs to undertake research aimed at resolving the gap, and the setting up of research based mechanisms to ensure access to new effective products for the treatment and prevention of poverty-related diseases.[6] However, given the number of diseases that are preventable, other factors that are blocking the access of patients to these products, such as cost of treatments to the individual, also need to be addressed, rather that just focusing on developing new drugs.[7] There is also a need to build the primary health care sector in developing countries. It has been shown that early detection and effective management of disease can be provided by appropriately-trained, non-physician, healthcare workers.[8]

Health expenditure[]

The gap between financial needs and financial means in low income countries can only be filled by donations. The average health expenditure per capita in western countries is estimated at $947 compared to $20 per capita in low income countries. To assist the world's poorest, health expenditure between $44–60 per capita is placed as a target.[9] This target is achieved by the contribution of 0.1% of advanced western countries gross national production (GNP) to fund global health, this recommendation was set by the WHO in 2001 and is estimated to save 8 million lives per year.[10]

Global research and development[]

Among other efforts to address this issue are recent proposals for a Global Research and Development (R&D) treaty, and the creation of the nonprofit pharmaceutical company OneWorld Health which develops new and affordable medicines for neglected diseases. A treaty creates a system that allows health research to come from contributions by all and therefore the sharing of benefits for all, improving the fairness and sustainability of global research and development.[11] In a positive development for the closing of the gap, in the 2012 London Declaration on Neglected Tropical Diseases many parties, including governments, funding organisations and drug companies, agreed to work towards the eradication of neglected tropical diseases.[12]


Despite the findings of the World Health Organization, and the disparity of curable diseases throughout developing and developed countries, some people[weasel words] believe the 10/90 gap is a myth.[13] They criticise the fact that simple medicines which stop curable and treatable conditions such as diarrhoea and malaria are available to these countries. The issue is not with the medicine, but with the ability for the affected to access it. Access to medicine can be inhibited by many circumstances such as poverty, strict government regime and inadequate healthcare systems and infrastructure.[13]

See also[]


  1. ^ "10/90 gap". Global Forum for Health Research. 2011. Retrieved April 16, 2015.[permanent dead link]
  2. ^ Luchetti, M. (2014). Global health and the 10/90 gap. British Journal of Medical Practitioners, 7(4), 4.
  3. ^ a b c Currat, L.J., Francisco, A., Al-Tuwaijri, S., Ghaffar, A., & Jupp, S. (2004). 10/90 report on health research 2003-2004. WHO Drug Information, 18(3), 243. Retrieved from http://announcementsfiles.cohred.org/gfhr_pub/assoc/s14789e/s14789e.pdf
  4. ^ Hotez P.J.; Ferris M.T. (2006). "The antipoverty vaccines". Vaccine. 26 (24): 5787–5799. doi:10.1016/j.vaccine.2006.05.008. PMID 16759763.
  5. ^ Haines, A., Kuruvilla, S., & Borchert, M. (2004). Bridging the implementation gap between knowledge and action for health. Bulletin of the World Health Organization, 82(10), 724–732.
  6. ^ Kilama W. L. (2009). "The 10/90 gap in sub-saharan africa: Resolving inequities in health research". Acta Tropica. 112: S8–S15. doi:10.1016/j.actatropica.2009.08.015. PMID 19695211.
  7. ^ Stevens, Philip (2004). Diseases of Poverty and the 10/90 Gap. London, UK.: International Policy Network. pp. 7–8.
  8. ^ Hunter, D.J.; Reddy, K.S. (2013). "Global health: Noncommunicable diseases". The New England Journal of Medicine. 369 (14): 1336–1343. doi:10.1056/NEJMra1109345. PMID 24088093.
  9. ^ Luchetti, Marco (2014). "Global Health and the 10/90 gap". British Journal of Medical Practitioners. ISSN 1757-8515. Archived from the original on 2015-03-26. Retrieved 10 April 2015.
  10. ^ World Health Organization (2001). Macroeconomics and Health: Investing in Health for Economic Development. Geneva: World Health Organization. pp. 7–11. ISBN 9789241545501.
  11. ^ Moon, Suerie (15 May 2012). "Innovation and Access to Medicines for Neglected Populations: Could a Treaty Address a Broken Pharmaceutical R&D System?". PLOS Medicine. 9 (5): e1001218. doi:10.1371/journal.pmed.1001218. PMC 3352855. PMID 22615544.
  12. ^ Liese, Bernhard H; Houghton, Natalia; Teplitskaya, Lyubov (2014). "Development assistance for neglected tropical diseases: Progress since 2009". International Health. 6 (3): 162–171. doi:10.1093/inthealth/ihu052. PMID 25096331.
  13. ^ a b Vidyasagar, D (2006). "Global notes: The 10/90 gap disparities in global health research". Journal of Perinatology. 26 (1): 55–56. doi:10.1038/sj.jp.7211402. PMID 16281051. S2CID 31057013.

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