|Place of origin||Germany|
|Case type||Rimless, bottleneck|
|Bullet diameter||.424 in (10.8 mm)|
|Neck diameter||.453 in (11.5 mm)|
|Shoulder diameter||.480 in (12.2 mm)|
|Base diameter||.495 in (12.6 mm)|
|Rim diameter||.495 in (12.6 mm)|
|Rim thickness||.051 in (1.3 mm)|
|Case length||2.677 in (68.0 mm)|
|Overall length||3.189 in (81.0 mm)|
|Rifling twist||1-16.53 in (420 mm)|
|Maximum pressure (CIP)||47,862 psi (330.00 MPa)|
|Source(s): Cartridges of the World.|
The 10.75x68mm Mauser was a popular big game cartridge with African and Indian hunters, it was used successfully on all dangerous game species up to and including elephant, although many experienced hunters considered it unsatisfactory for the latter.
John "Pondoro" Taylor stated the 10.75x68mm Mauser was undoubtedly one of the most widely used cartridges for hunting in Africa due to its low chamber pressure, the light weight of rifles chambering the cartridge, usually between 7.25–7.5 pounds (3.29–3.40 kg), and the low cost of the early German Mauser rifles. Taylor was very critical of the cartridge due to its poor sectional density and as a result poor penetration. Taylor stated the fully jacketed versions lacked the penetration for frontal head shots on elephant or shoulder shots on buffalo and the expanding bullets were inadequate on lion and eland.
One prominent user of the 10.75x68mm Mauser was Donald Anderson, son of Kenneth Anderson, who used a rifle chambering this cartridge to hunt almost all Indian dangerous game species and who stated it was far superior to his father's .405 Winchester.