1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (pentalenolactone-D forming)

Pentalenolactone D synthase
Identifiers
EC no.1.14.13.170
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Pentalenolactone D synthase (EC 1.14.13.170, penE (gene), pntE (gene)) is an enzyme with systematic name 1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (pentalenolactone-D forming).[1] This enzyme catalyses the following chemical reaction

1-deoxy-11-oxopentalenate + NADPH + H+ + O2 pentalenolactone D + NADP+ + H2O

Pentalenolactone D synthase is a FAD-dependent oxygenase.

References[]

  1. ^ Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE (March 2011). "Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone". Biochemistry. 50 (10): 1739–54. doi:10.1021/bi1019786. PMC 3051010. PMID 21250661.

External links[]