Pentagalloyl glucose can undergo oxidation reactions which are depending on the pH.
Pentagalloyl glucose has been studied for its potential use as an antimicrobial, anti-inflammatory, anticarcinogenic, antidiabetic, and antioxidant. It has also been studied for radioprotection. This compound helps stabilize the elastin and collagen in vascular tissues and restores the biomechanical properties of arterial ECM. In addition, pentagalloyl glucose has shown to reduce arterial calcification and helps promote extracellular matrix preservation in animal models of abdominal aortic aneurysm.In vitro studies with mouse C2C12 myoblast cells have shown the PGG helps in lowering reactive oxygen species (ROS) and matrix metalloproteinase-2 (MMP-2) expression in a dose-dependent manner. 
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