(S)-methylmalonyl-CoA hydrolase

(S)-methylmalonyl-CoA hydrolase
Identifiers
EC no.3.1.2.17
CAS no.87928-03-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a (S)-methylmalonyl-CoA hydrolase (EC 3.1.2.17) is an enzyme that catalyzes the chemical reaction

(S)-methylmalonyl-CoA + H2O methylmalonate + CoA

Thus, the two substrates of this enzyme are (S)-methylmalonyl-CoA and H2O, whereas its two products are methylmalonate and CoA.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is (S)-methylmalonyl-CoA hydrolase. This enzyme is also called D-methylmalonyl-coenzyme A hydrolase. This enzyme participates in propanoate metabolism.

References[]