|carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase|
|Locus||Chr. 2 p22-p21|
Dihydroorotase (EC 18.104.22.168, carbamoylaspartic dehydrase, dihydroorotate hydrolase) is an enzyme which converts carbamoyl aspartic acid into 4,5-dihydroorotic acid in the biosynthesis of pyrimidines. It forms a multifunctional enzyme with carbamoyl phosphate synthetase and aspartate transcarboymalase.