(-)-sabinene synthase

(-)-sabinene synthase (EC 4.2.3.109) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, (-)-sabinene-forming).^[1]^[2] This enzyme catalyses the following chemical reaction

\rightleftharpoons

This enzyme requires Mg²⁺.

References[]

^ Savage TJ, Hatch MW, Croteau R (February 1994). "Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase". The Journal of Biological Chemistry. 269 (6): 4012–20. PMID 8307957.
^ Peters RJ, Croteau RB (September 2003). "Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases". Archives of Biochemistry and Biophysics. 417 (2): 203–11. doi:10.1016/s0003-9861(03)00347-3. PMID 12941302.

(-)-sabinene+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)

v t e Carbon–oxygen lyases (EC 4.2) (primarily dehydratases)
4.2.1: Hydro-Lyases	Carbonic anhydrase Fumarase Aconitase Enolase Alpha Enolase 2 Enoyl-CoA hydratase/3-Hydroxyacyl ACP dehydrase Methylglutaconyl-CoA hydratase Tryptophan synthase Cystathionine beta synthase Porphobilinogen synthase 3-Isopropylmalate dehydratase Urocanase Uroporphyrinogen III synthase Nitrile hydratase
4.2.2: Acting on polysaccharides	Hyaluronate lyase
4.2.3: Acting on phosphates	Threonine synthase
4.2.99: Other	Carboxymethyloxysuccinate lyase Hydroperoxide lyase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)