(-)-camphene synthase

(-)-camphene synthase
EC no.
IntEnzIntEnz view
ExPASyNiceZyme view
MetaCycmetabolic pathway
PDB structuresRCSB PDB PDBe PDBsum

(-)-camphene synthase (EC, CS) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing, (-)-camphene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction

geranyl diphosphate (-)-camphene + diphosphate

(-)-Camphene is the major product in Abies grandis (grand fir) with traces of other monoterpenoids.


  1. ^ Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R (August 1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Archives of Biochemistry and Biophysics. 368 (2): 232–43. doi:10.1006/abbi.1999.1332. PMID 10441373.
  2. ^ Huber DP, Philippe RN, Godard KA, Sturrock RN, Bohlmann J (June 2005). "Characterization of four terpene synthase cDNAs from methyl jasmonate-induced Douglas-fir, Pseudotsuga menziesii". Phytochemistry. 66 (12): 1427–39. doi:10.1016/j.phytochem.2005.04.030. PMID 15921711.
  3. ^ Hyatt DC, Croteau R (July 2005). "Mutational analysis of a monoterpene synthase reaction: altered catalysis through directed mutagenesis of (-)-pinene synthase from Abies grandis". Archives of Biochemistry and Biophysics. 439 (2): 222–33. doi:10.1016/j.abb.2005.05.017. PMID 15978541.
  4. ^ Falara V, Akhtar TA, Nguyen TT, Spyropoulou EA, Bleeker PM, Schauvinhold I, Matsuba Y, Bonini ME, Schilmiller AL, Last RL, Schuurink RC, Pichersky E (October 2011). "The tomato terpene synthase gene family". Plant Physiology. 157 (2): 770–89. doi:10.1104/pp.111.179648. PMC 3192577. PMID 21813655.

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