(-)-Isopiperitenone reductase

(-)-isopiperitenone reductase
Identifiers
EC number1.3.1.82
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

(-)-Isopiperitenone reductase (EC 1.3.1.82) is an enzyme with systematic name (+)-cis-isopulegone:NADP+ oxidoreductase.[1][2] It catalyses the following chemical reaction:

(+)-cis-isopulegone + NADP+ (-)-isopiperitenone + NADPH + H+

The reaction occurs in the opposite direction.

References[]

  1. ^ Croteau R, Venkatachalam KV (September 1986). "Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (-)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita)". Archives of Biochemistry and Biophysics. 249 (2): 306–15. doi:10.1016/0003-9861(86)90007-x. PMID 3755881.
  2. ^ Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R (October 2003). "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics. 418 (1): 80–92. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086.

External links[]