Chemical structure of hopeaphenol
Other names
3D model (JSmol)
Molar mass 906.940 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Hopeaphenol is a stilbenoid. It is a resveratrol tetramer. It has been first isolated from Dipterocarpaceae[1] like Shorea ovalis.[2] It has also been isolated from wines from North Africa.[3]

It shows an opposite effect to vitisin A on apoptosis of myocytes isolated from adult rat heart.[4]

See also[]


  1. ^ The structure of hopeaphenol. P. Coggon, T. J. King and S. C. Wallwork, Chem. Commun. (London), 1966, pages 439-440, doi:10.1039/C19660000439
  2. ^ The Isolation of Hopeaphenol, a Tetramer Stilbene, from Shorea ovalis Blume. Advances in Natural & Applied Sciences, January–April 2009, Volume 3, Issue 1, page 107 (abstract)
  3. ^ Habiba Amira Guebailia; Kleopatra Chira; Tristan Richard; Teguiche Mabrouk; Aurélie Furiga; Xavier Vitrac; Jean-Pierre Monti; Jean-Claude Delaunay; Jean-Michel Mérillon (2006). "Hopeaphenol: The First Resveratrol Tetramer in Wines from North Africa". J. Agric. Food Chem. 54 (25): 9559–9564. doi:10.1021/jf062024g. PMID 17147446.
  4. ^ Seya, Kazuhiko; Kanemaru, Kouta; Sugimoto, Chiharu; Suzuki, Megumi; Takeo, Teruko; et al. (2008-10-16). "Opposite Effects of Two Resveratrol (trans-3,5,4′-Trihydroxystilbene) Tetramers, Vitisin A and Hopeaphenol, on Apoptosis of Myocytes Isolated from Adult Rat Heart". Journal of Pharmacology and Experimental Therapeutics. American Society for Pharmacology & Experimental Therapeutics (ASPET). 328 (1): 90–98. doi:10.1124/jpet.108.143172. ISSN 0022-3565.