(-)-(4S)-beta-phellandrene synthase

(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing)
EC no.
CAS no.137010-34-5
IntEnzIntEnz view
ExPASyNiceZyme view
MetaCycmetabolic pathway
PDB structuresRCSB PDB PDBe PDBsum

(4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing) (EC, phellandrene synthase, (−)-beta-phellandrene synthase, (−)-(4S)-beta-phellandrene synthase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase (cyclizing; (4S)-beta-phellandrene-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction

geranyl diphosphate (4S)-beta-phellandrene + diphosphate

This enzyme requires ion Mn2+.


  1. ^ Savage TJ, Hatch MW, Croteau R (February 1994). "Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase". The Journal of Biological Chemistry. 269 (6): 4012–20. PMID 8307957.
  2. ^ Bohlmann J, Phillips M, Ramachandiran V, Katoh S, Croteau R (August 1999). "cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis)". Archives of Biochemistry and Biophysics. 368 (2): 232–43. doi:10.1006/abbi.1999.1332. PMID 10441373.
  3. ^ Wagschal K, Savage TJ, Croteau R (1991). "Isotopically sensitive branching as a tool for evaluating multiple product formation by monoterpene cyclases". Tetrahedron. 31: 5933–5944. doi:10.1016/s0040-4020(01)86486-3.
  4. ^ LaFever RE, Croteau R (March 1993). "Hydride shifts in the biosynthesis of the p-menthane monoterpenes alpha-terpinene, gamma-terpinene, and beta-phellandrene". Archives of Biochemistry and Biophysics. 301 (2): 361–6. doi:10.1006/abbi.1993.1156. PMID 8460944.

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