This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is [(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase. Other names in common use include XEG, xyloglucan endo-beta-1,4-glucanase, xyloglucanase, xyloglucanendohydrolase, XH, and 1,4-beta-D-glucan glucanohydrolase.
Family 12 was first identified in plant pathogens by discovery in Phytophthora spp.
Grishutin SG, Gusakov AV, Markov AV, Ustinov BB, Semenova MV, Sinitsyn AP (November 2004). "Specific xyloglucanases as a new class of polysaccharide-degrading enzymes". Biochimica et Biophysica Acta (BBA) - General Subjects. 1674 (3): 268–81. doi:10.1016/j.bbagen.2004.07.001. PMID15541296.
Costanzo S, Ospina-Giraldo MD, Deahl KL, Baker CJ, Jones RW (October 2006). "Gene duplication event in family 12 glycosyl hydrolase from Phytophthora spp". Fungal Genetics and Biology. 43 (10): 707–14. doi:10.1016/j.fgb.2006.04.006. PMID16784880.